|
If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.
It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.
Wiley InterScience | ||||||||||||
  Journal of Cosmetic DermatologyVolume 6 Issue 1, Pages 14 - 19 Published Online: 5 Mar 2007 © 2009 Wiley Periodicals, Inc. The official journal of the International Academy of Cosmetic Dermatology
Abstract | References | Full Text: HTML, PDF (Size: 187K) | Related Articles | Citation Tracking  Original Contribution Effect of pre-treatment of almond oil on ultraviolet B–induced cutaneous photoaging in mice Copyright © 2007 Blackwell Publishing KEYWORDS almond oil • cutaneous photoaging • photoprotective effect • ultraviolet light Summary
Background Ultraviolet (UV) radiation has been implicated in photoaging and various types of skin carcinomas. Although the human skin has evolved several defense mechanisms to survive the insults of actinic damage like keratinization, melanin pigmentation, etc., it is still subjected to the harmful effects of sunlight. Aims In this study, the role of almond oil in reducing the degradative changes induced in skin upon exposure to UV radiation was investigated. Methods Mice were divided in four groups of 20 animals. Group I was the control group. Group II was negative control, which received almond oil treatment alone. Group III was exposed to UV radiation only and Group IV received both UV treatment and almond oil treatment. Visible skin grading assessed the changes based on a rating scale, biochemical tests (glutathione estimation and lipid peroxidation), and histopathologic studies. Results Upon exposure of mice to UV radiation, it was found that pronounced visible skin changes were seen after 12 weeks of exposure. The results of the biochemical tests, glutathione estimation, and lipid peroxidation showed that almond oil reduced the effect of UV light–induced photoaging on the skin. Histopathologic studies also indicated a photoprotective effect of almond oil on the skin after UV exposure. Conclusions It was concluded that topical almond oil is capable of preventing the structural damage caused by UV irradiation and it was also found useful in decelerating the photoaging process. Accepted for publication August 6, 2006 | 
|
