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Wiley InterScience | ||||||||||||
  Influenza and Other Respiratory VirusesVolume 1 Issue 2, Pages 65 - 69 Published Online: 25 May 2007 © 2010 Blackwell Publishing Ltd The Official Journal of the International Society for Influenza and other Respiratory Virus Diseases
Abstract | References | Full Text: HTML, PDF (Size: 538K) | Related Articles | Citation Tracking  Original Article Avian influenza and poultry workers, Peru, 2006 Copyright 2007 The Authors Journal Compilation 2007 Blackwell Publishing Ltd KEYWORDS Human • influenza • influenza in birds • occupational exposure • Peru • poultry • zoonoses ABSTRACTBackground Currently numerous countries in Asia, Africa and Europe are encountering highly pathogenic avian influenza (AI) infections in poultry and humans. In the Americas, home of the world's largest poultry exporters, contingency plans are being developed and evaluated in preparation for the arrival of these viral strains. Objectives With this cross-sectional study, to our knowledge the first in its kind in Central or South America, we sought to learn whether Peruvian poultry workers had evidence of previous AI infection and if so, to determine the risk factors for infection. Methods We performed a cross-sectional seroprevalence study among 149 workers on a Peruvian poultry farm (132 exposed to poultry and 17 non-exposed controls), serum samples were tested for human influenza virus exposure using a hemagglutination inhibition (HI) assay. Microneutralization assays were performed on all serum samples to detect antibodies against prototypic AI strains H4 through H12. Results Using multivariate proportional odds modeling we found that the prevalence of elevated titers against AI viruses was low in both groups, exposed and non-exposed controls. Conclusions No evidence of previous AI infection among Peruvian poultry workers was found in this first cross-sectional study performed in South America. This first occupational study of AI in Latin America was encouraging, but it likely reflects the sector of poultry production with higher biosecurity. Accepted 24 April 2007. | 
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