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Type 1 diabetes and prolonged fasting
J. Reiter, I. D. Wexler, N. Shehadeh*, A. Tzur and D. Zangen
Division of Paediatric Endocrinology, Department of Paediatrics, Mt Scopus Campus, Hadassah Hebrew University Medical Centre, Jerusalem,  *Department of Paediatrics, Rambam Medical Centre, Rapaport School of Medicine, Haifa and  Darom Diabetes Clinic, Klalit Health Services, Jerusalem, Israel
Correspondence to: Dr David Zangen, Division of Paediatric Endocrinology, Department of Paediatrics, Hadassah University Medical Centre, Jerusalem, Israel 91240. E-mail: zangend@hadassah.org.il

J.R. and I.D.W. contibuted equally to this study.

Copyright © 2007 The Authors.
Journal compilation © 2007 Diabetes UK.
KEYWORDS
IDDM • fast day • fasting

Diabet. Med. (2007)

ABSTRACT

Aims  Fasting is common in several religions. The aims of this study were to determine if prolonged fasting (> 25 h) is safe for individuals with Type 1 diabetes and to identify factors associated with success.

Methods  Patients intending to fast were instructed on insulin dose adjustments, frequent glucose monitoring and when to terminate the fast using a standard protocol. Clinical and epidemiological factors were recorded and a comparison was made between successful and unsuccessful fasters.

Results  Of 56 subjects who intended to fast, 37 (65%) were successful. Individuals terminated their fast in the presence of either hypoglycaemia or hyperglycaemia and adherence to the protocol was high. There were no serious side-effects of fasting. Successful fasters had greater reductions in insulin dosage and higher HbA1c. There were no differences between individuals taking intermittent insulin injections and those with continuous infusion pumps.

Conclusions  Persons with Type 1 diabetes can participate safely in prolonged fasts provided they reduce their usual insulin dose significantly and adhere to guidelines regarding glucose monitoring and indications for terminating fasting.


Accepted 16 October 2006

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1464-5491.2007.02098.x About DOI

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