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Wiley InterScience | ||||||||||||||||||
 Journal of Fish DiseasesVolume 30 Issue 9, Pages 511 - 531 Special Issue: Special Alphavirus issue Published Online: 20 Aug 2007 © 2010 Blackwell Publishing Ltd
Abstract | References | Full Text: HTML, PDF (Size: 1505K) | Related Articles | Citation Tracking  Review Alphavirus infections in salmonids – a review Copyright 2007 The Authors. Journal compilation 2007 Blackwell Publishing Ltd KEYWORDS alphavirus • pancreas disease • salmonids • sleeping disease Abstract
The first alphavirus to be isolated from fish was recorded in 1995 with the isolation of salmon pancreas disease virus from Atlantic salmon, Salmo salar L., in Ireland. Subsequently, the closely related sleeping disease virus was isolated from rainbow trout, Oncorhynchus mykiss (Walbaum), in France. More recently Norwegian salmonid alphavirus (SAV) has been isolated from marine phase production of Atlantic salmon and rainbow trout in Norway. These three viruses are closely related and are now considered to represent three subtypes of SAV, a new member of the genus Alphavirus within the family Togaviridae. SAVs are recognized as serious pathogens of farmed Atlantic salmon and rainbow trout in Europe. This paper aims to draw together both historical and current knowledge of the diseases caused by SAVs, the viruses, their diagnosis and control, and to discuss the differential diagnosis of similar pathologies seen in cardiomyopathy syndrome and heart and skeletal muscle inflammation of Atlantic salmon. Received: 16 January 2007 Revision received and accepted: 18 April 2007 | 
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