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Wiley InterScience | ||
![]() Dermatologic TherapyVolume 20 Issue 4, Pages 277 - 287 Published Online: 25 Oct 2007 © 2010 Wiley Periodicals, Inc.
Abstract | References | Full Text: HTML, PDF (Size: 102K) | Related Articles | Citation Tracking Off-label uses of rituximab in dermatology This paper is completely self-generated and has not received any outside funding. This paper only reflects the views of its authors. Dr Heffernan has been a paid investigator, lecturer and/or consultant for Abbott, Amgen, Biogen-IDEC, Centocor and Genentech. Contents of this manuscript were presented at the 64th Annual Meeting of the American Academy of Dermatology. Copyright © Blackwell Publishing, Inc., 2007 KEYWORDS biologics • rituximab ABSTRACTABSTRACT: Since its approval in 1997 by the FDA, rituximab has been approved for use in certain B-cell lymphomas and treatment-resistant rheumatoid arthritis. Over the past 10 years, many case reports have indicated rituximab's efficacy in a number of inflammatory conditions in dermatology. This article includes a review of the mechanism of action, dosing, and side effect profile, as well as a review of the current literature on off-label uses of the CD20 |