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Wiley InterScience | ||||||||||||
  FEMS Microbiology LettersVolume 274 Issue 1, Pages 30 - 34 Published Online: 15 Jun 2007 © 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved Published on behalf of the Federation of European Microbiological Societies
Abstract | References | Full Text: HTML, PDF (Size: 94K) | Related Articles | Citation Tracking  A hyperconserved protein in Prochlorococcus and marine Synechococcus Copyright © 2007 Federation of European Microbiological Societies KEYWORDS cyanobacteria • ORFan • sequence conservation ABSTRACTAn ORF (encoding a hyperconserved protein of unknown function) in Prochlorococcus/marine Synechococcus genomes that is 100% conserved on the amino acid level but lacks homologs outside this group is described here. Such conservation of an uncharacterized group-specific gene is unusual, and unexpected given the extensive genomic divergence of this group at other loci. Comparative analyses indicate that the hyperconserved protein, which may be involved in interactions with nucleic acids, is under stabilizing selection and has resided in these genomes since the last common ancestor of the group. Received 12 March 2007; revised 14 May 2007; accepted 14 May 2007. | 
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