Anticandidial activity of some essential oils of a mega biodiversity hotspot in India

doi:10.1111/j.1439-0507.2006.01332.x

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Wiley InterScience

Mycoses

Volume 50 Issue 2, Pages 121 - 124

Published Online: 12 Dec 2006

Published on behalf of the Deutschsprachige Mykologische Gesellschaft

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Original Article

Anticandidial activity of some essential oils of a mega biodiversity hotspot in India

B. K. Dutta, S. Karmakar, A. Naglot, J. C. Aich and M. Begam

Biotechnology Division, Defence Research Laboratory, Tezpur, Assam, India

Correspondence to B. K. Dutta, Defence Research Laboratory, Post Bag No. 2, Tezpur 784 001, Assam, India.
Tel.: +91 03712 258447. Fax: +91 03712 258534.
E-mail: biiplab@yahoo.co.in

KEYWORDS

essential oils • antibiotics • zone of inhibition • least significance difference • Candida albicans

Summary

Six essential oils viz. Eucalyptus citriodora, Cymbopogon citratus, Callistemon lanceolatus, Cinnamomum camphora, Citrus limon, Tagetes petula, as well as two standard antibiotics, miconazole and clotrimazole, were tested in vitro for their anticandidial activity. All these essential oils exhibited higher activity than the two synthetic antibiotics. Highest zone of inhibition was recorded in E. citriodora (8.50 mm μl⁻¹) followed by C. lanceolatus (5.63 mm μl⁻¹) establishing their promising anticandidial potential.