Electrostimulating device in the management of xerostomia

doi:10.1111/j.1601-0825.2006.01268.x

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Wiley InterScience

Oral Diseases

Volume 13 Issue 2, Pages 206 - 213

Published Online: 31 Aug 2006

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ORIGINAL ARTICLE

Electrostimulating device in the management of xerostomia

FP Strietzel ¹ , R Martín-Granizo ² , S Fedele ^3,5 , L Lo Russo ³ , M Mignogna ³ , PA Reichart ¹ , A Wolff ⁴

¹ Abteilung für Oralchirurgie und Zahnärzliche Röntgenologie, Charité– Universitätsmedizin Berlin, Campus Virchow-Klinikum, Germany ; ² Servicio de Cirugla Oral y Maxilofacial, Hospital Clínico San Carlos, Madrid, Spain ; ³ Dipartmento di Scienze Odontostamatologiche e Maxillo-Facciali, Università di Napoli Federico II, Italy ; ⁴ Saliwell Ltd, Assuta Hospital, Tel Aviv, Israel ; ⁵ Oral Medicine Unit, Eastman Dental Institute for Oral Health Care Sciences, University of London, UK

Correspondence to Dr Andy Wolff, 2 Hatamar St., Harutzim 60917, Israel. Tel: 00972-9-746-1630, Fax: 00972-9-746-3083, E-mail: awolff@zahav.net.il

KEYWORDS

dry mouth • salivary glands • salivary flow rate • Sjögren's syndrome

Oral Diseases (2007) 13, 206–213

ABSTRACT

Introduction: The present study was undertaken to evaluate the safety and effectiveness of a recently developed electrostimulating device mounted on an individualized intra-oral removable appliance.

Materials and methods: The device, containing electrodes, a wetness sensor, an electronic circuit and a power source, was tested on patients with xerostomia in a crossover, randomized, sham-controlled, double-blinded, multicenter study. Electrical stimulation and also sham were delivered during 10 min to the oral mucosa, in the mandibular third molar region. Oral dryness was measured by the sensor. As the primary outcome, sensor dryness and xerostomia symptom changes as a result of device wearing were assessed, and compared between active and sham modes. In addition, side-effects were recorded.

Results: Electrostimulation resulted in a significant decrease in sensor dryness, leading to a beneficial effect on patients' subjective condition. No significant side-effects were observed.

Received 24 August 2005; revised 20 December 2005, 19 January 2006, 25 February 2006; accepted 26 February 2006

DIGITAL OBJECT IDENTIFIER (DOI)

10.1111/j.1601-0825.2006.01268.x About DOI

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