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Wiley InterScience

Journal of Applied Microbiology

Journal of Applied Microbiology

Volume 100 Issue 6, Pages 1171 - 1185

Published Online: 5 Apr 2006

Journal compilation © 2010 The Society for Applied Microbiology



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REVIEW ARTICLE
Probiotics and their fermented food products are beneficial for health
S. Parvez 1*, K.A. Malik 2 , S. Ah Kang 3 and H.-Y. Kim 1
  1 Helix Pharms Co. Ltd, Kyung-Hee University, and Department of Biological Sciences of Oriental Medicine, Graduate School of Interdepartmental Studies, Institute of Oriental Medicines, Kyung-Hee University, Dongdaemoon-gu, Seoul, Korea
  2 PAEC, Islamabad, Pakistan
  3 Department of Molecular Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Gwangjin-gu, Seoul, Korea
Correspondence to Hong-Yeoul Kim, Institute of oriental Medicine, Kyung-Hee University, Hoegi-dong, Dongdaemoon-gu, Seoul 130-701, Korea.
E-mail: hyk@khu.ac.kr

  *Permanent address: NIBGE, P.O. Box 577, Faislabad, Pakistan.

Copyright 2006 The Authors Journal compilation 2006 The Society for Applied Microbiology
KEYWORDS
Bacteriocins • Bifidobacterium SP • lactic acid bacteria • Lactobacillus acidophilus • Mutagens • Probiotics

Abstract

AbstractIntroductionWork of probioticsHistoryComposition of probiotic preparationsReferences

Probiotics are usually defined as microbial food supplements with beneficial effects on the consumers. Most probiotics fall into the group of organisms' known as lactic acid-producing bacteria and are normally consumed in the form of yogurt, fermented milks or other fermented foods. Some of the beneficial effect of lactic acid bacteria consumption include: (i) improving intestinal tract health; (ii) enhancing the immune system, synthesizing and enhancing the bioavailability of nutrients; (iii) reducing symptoms of lactose intolerance, decreasing the prevalence of allergy in susceptible individuals; and (iv) reducing risk of certain cancers. The mechanisms by which probiotics exert their effects are largely unknown, but may involve modifying gut pH, antagonizing pathogens through production of antimicrobial compounds, competing for pathogen binding and receptor sites as well as for available nutrients and growth factors, stimulating immunomodulatory cells, and producing lactase. Selection criteria, efficacy, food and supplement sources and safety issues around probiotics are reviewed. Recent scientific investigation has supported the important role of probiotics as a part of a healthy diet for human as well as for animals and may be an avenue to provide a safe, cost effective, and 'natural' approach that adds a barrier against microbial infection. This paper presents a review of probiotics in health maintenance and disease prevention.


2005/1024: received 9 September 2005, revised 22 December 2005 and accepted 24 January 2006

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1365-2672.2006.02963.x About DOI

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