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Wiley InterScience | |||||||||||||||||||
  International Journal of Experimental PathologyVolume 87 Issue 5, Pages 325 - 341 Published Online: 25 Aug 2006 Journal compilation © 2010 Blackwell Publishing Ltd
Abstract | References | Full Text: HTML, PDF (Size: 551K) | Related Articles | Citation Tracking  CURRENT STATUS REVIEW Human gastrointestinal nematode infections: are new control methods required? Copyright 2006 Blackwell Publishing Ltd KEYWORDS anthelmintic • control • gastrointestinal nematodes • human • plant cysteine proteinases • resistance Summary
Gastrointestinal (GI) nematode infections affect 50% of the human population worldwide, and cause great morbidity as well as hundreds of thousands of deaths. Despite modern medical practices, the proportion of the population infected with GI nematodes is not falling. This is due to a number of factors, the most important being the lack of good healthcare, sanitation and health education in many developing countries. A relatively new problem is the development of resistance to the small number of drugs available to treat GI nematode infections. Here we review the most important parasitic GI nematodes and the methods available to control them. In addition, we discuss the current status of new anthelmintic treatments, particularly the plant cysteine proteinases from various sources of latex-bearing plants and fruits. Received for publication: 9 February 2006 Accepted for publication: 22 June 2006 | 
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