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Wiley InterScience | |||||||
  Tissue AntigensVolume 68 Issue 5, Pages 450 - 452 Published Online: 7 Nov 2006 © 2010 John Wiley & Sons A/S The official journal of the European Federation for Immunogenetics
Abstract | References | Full Text: HTML, PDF (Size: 177K) | Related Articles | Citation Tracking  BRIEF COMMUNICATION The LRC haplotype project: a resource for killer immunoglobulin-like receptor-linked association studies Copyright 2006 The Authors Journal compilation KEYWORDS haplotypes • killer immunoglobulin-like receptor • leucocyte receptor complex • polymorphism • single nucleotide Abstract
There is increasing evidence for epistatic interactions between gene products (e.g. KIR) encoded within the Leukocyte Receptor Complex (LRC) with those (e.g. HLA) of the Major Histocompatibility Complex (MHC), resulting in susceptibility to disease. Identification of such associations at the DNA level requires comprehensive knowledge of the genetic variation and haplotype structure of the underlying loci. The LRC haplotype project aims to provide this knowledge by sequencing common LRC haplotypes. Received 1 September 2006; accepted 11 September 2006 | 
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