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Wiley InterScience

Sleep and Biological Rhythms

Sleep and Biological Rhythms

Volume 4 Issue 2, Pages 193 - 195

Published Online: 9 Jun 2006

Journal compilation © 2009 Japanese Society of Sleep Research



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SHORT PAPER
A case of restless legs syndrome successfully treated with quetiapine
Shuken BOKU, Masashi HIROTA, Hisako YOSHIDA, Hiroshi HOMMA, Shunji IWASAKI and Shigehiro MATSUBARA
Department of psychiatry and neurology, National Hospital Organization Obihiro hospital, Obihiro, Japan
Correspondence to  Dr Shuken Boku, Department of psychiatry and neurology, National hospital organization Obihiro hospital, Nishi 18 jyo Kita 2 chome, Obihiro, 080-8518, Japan. Email: shuboku@mtj.biglobe.ne.jp
Copyright © 2006 The Authors; Journal compilation © 2006 Japanese Society of Sleep Research
KEYWORDS
antipsychotic drug • dopamine • quetiapine • restless legs syndrome

Abstract

AbstractINTRODUCTIONCASE REPORTDISCUSSIONREFERENCES

Restless legs syndrome is generally treated with benzodiazepines, dopamine agonists or opioids; however, it is often resistant to these drugs. Here we report a case of restless legs syndrome that was successfully treated with quetiapine. The patient was a 17-year-old woman. Although her symptoms were not improved by treatment with clonazepam or cabergoline, the additional administration of quetiapine, one of the second-generation antipsychotic drugs, induced remarkable improvement in her symptoms. Although antipsyochotic drugs sometimes induce or complicate restless legs syndrome, this case seems to suggest that quetiapine can be effective on restless legs syndrome.


Accepted for publication 1 February 2006

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1479-8425.2006.00216.x About DOI

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