|
If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.
It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.
Wiley InterScience | |||||||||||||||||
  Tropical Medicine & International HealthVolume 11 Issue 4, Pages 386 - 397 Published Online: 23 Mar 2006 © 2010 Blackwell Publishing Ltd
Abstract | References | Full Text: HTML, PDF (Size: 125K) | Related Articles | Citation Tracking  The effect of Plasmodium falciparum on cognition: a systematic review Copyright 2006 Blackwell Publishing Ltd KEYWORDS
Plasmodium falciparum
• malaria • cognition • systematic review Summary
Objective Systematic review to investigate the relationship between Plasmodium falciparum infection and cognitive function. Method We searched MEDLINE, EMBASE and PsycINFO, and hand-searched journals and PhD theses. The inclusion criteria were (1) use of standardized tests for the specific populations and/or appropriate controls; (2) clear differentiation between children and adults. Eighteen studies were eligible, of which three gave information on all cognitive domains considered in the review. Results Deficits in attention, memory, visuo-spatial skills, language and executive functions may occur after malaria infection. These deficits are not only caused by cerebral falciparum malaria, but also appear to occur in less severe infections. P. falciparum seems to affect the brain globally, not in a localised fashion. Outcome depends on both biological and social risk factors. Conclusion Future research should seek to establish the extent of these cognitive deficits using culturally appropriate techniques and well-defined criteria of disease. | 
|
| |||||||||||||||
|
|||||||||||||||||
|
