|
If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.
It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.
Wiley InterScience | ||
  Journal of Nursing ScholarshipVolume 37 Issue 4, Pages 315 - 321 Published Online: 10 Nov 2005 © 2009 Sigma Theta Tau International Published with Sigma Theta Tau International, Honor Society of Nursing
Abstract | References | Full Text: HTML, PDF (Size: 104K) | Related Articles | Citation Tracking  Genomics for Health Genomics and Cardiovascular Disease Copyright 2005 Sigma Theta Tau International KEYWORDS
genomics
•
cardiovascular disease
•
cardiomyopathy
Journal of Nursing Scholarship, 2005; 37:4, 315-321. ©2005 Sigma Theta Tau International. ABSTRACTPurpose: To describe genetic knowledge and discovery in the area of cardiovascular disease (CVD) and to discuss how these new advances will influence the clinical care of affected people. Organizing Framework: A selective review of the literature is presented on the disease mechanism of both the Mendelian and multifactorial genetic cardiovascular conditions. A case study approach is used to illustrate how the genetic paradigm affects the healthcare experience of a family affected with familial hypertrophic cardiomyopathy. Findings: The current state of CVD treatment remains complex. An understanding of genomic concepts and a genome-based approach is necessary to determine: (a) the risk of CVD susceptibility beyond traditional risk factors; (b) early detection of illness; (c) response to treatment; and (d) molecular taxonomy of the disease. Conclusions: The results of genetic research, education, and teaching will lead to a new understanding of genes and pathways, resulting in powerful new therapeutic approaches to CVD. The challenge is to translate genetic discoveries into clinical practice that ultimately leads to preventing CVD and reducing mortality. Accepted for publication May 3, 2005. |
