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Wiley InterScience | ||||||
  Internal Medicine JournalVolume 35 Issue 1, Pages 45 - 49 Published Online: 13 Jan 2005 Journal compilation © 2009 Royal Australasian College of Physicians The Official Journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP)
Abstract | References | Full Text: HTML, PDF (Size: 610K) | Related Articles | Citation Tracking  Clinical Perspectives Modern management of portal hypertension Funding: None Potential conflicts of interest: None Copyright 2005 Royal Australasian College of Physicians KEYWORDS portal hypertension • variceal bleeding • hepatic venous pressure gradient • prophylaxis ABSTRACTAbstractThe development of portal hypertension plays a major role in the pathogenesis of many of the complications of chronic liver disease. In developed countries, most patients with portal hypertension have cirrhosis, and, in this condition, portal pressure is elevated as a result of both an increase in hepatic resistance to portal perfusion and increased mesenteric blood flow. Bleeding from oesophageal varices is a major cause of mortality in patients with significant portal hypertension. This review concentrates on the recognition, prevention and acute management of this life threatening complication of cirrhosis. (Intern Med J 2005; 35: 45–49) Received 7 May 2004; accepted 6 September 2004. | 
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