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Wiley InterScience

Journal of Paediatrics and Child Health

Journal of Paediatrics and Child Health

Volume 42 Issue 7-8, Pages 472 - 473

Published Online: 20 Jul 2006

Journal compilation © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians)



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CASE NOTE
Methimazole-induced toxic epidermal necrolysis in a 12-year-old girl
Katarzyna Ziora, 1 Joanna Oswiecimska, 1 Katarzyna Broll-Waska, 1 Maria Szczepanska, 1 Krystyna Szprynger, 1 Wojciech Pieniazek, 2 Malgorzata Pindycka-Piaszczynska, 3 Stanislaw Sakiel 4 and Marek Kawecki 4
 Departments of 1Paediatric Nephrology and Endocrinology,   2 Gastroenetrology, Allergology and Developmental Disorders,   3 Dermatology, Silesian Medical University, Zabrze and   4 Silesian Burns Centre, Siemianowice Slaskie, Poland
Correspondence to  Dr Joanna Oswiecimska, Department of Paediatric Nephrology and Endocrinology, Silesian Medical University ul. 3-Maja 13/15, 41-800 Zabrze, Poland. Fax: +48 32 271 8710; email: endo_dz_zabrze@wp.pl
Copyright 2006 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
KEYWORDS
children • hyperthyreosis • thiamazole • toxic epidermal necrolysis syndrome.

ABSTRACT

Abstract:  We report a 12-year-old girl with hyperthyreosis who presented methamazole-induced toxic epidermal necrolysis (TEN). The patient's past history suggests a presence of autoimmune disease. To our knowledge it is the first report describing such an adverse effect of methimazole.


Accepted for publication 1 March 2006.

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1440-1754.2006.00901.x About DOI

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