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Wiley InterScience | |||||||||||||
  Journal of the European Academy of Dermatology and VenereologyVolume 18 Issue 3, Pages 337 - 339 Published Online: 15 Apr 2004 Journal compilation © 2010 European Academy of Dermatology and Venereology Published on behalf of the European Academy of Dermatology and Venereology
Abstract | References | Full Text: HTML, PDF (Size: 127K) | Related Articles | Citation Tracking  CASE REPORT Pyogenic granulomas following topical application of tretinoin Copyright © 2004 European Academy of Dermatology and Venereology KEYWORDS acne • pyogenic granuloma • tretinoin ABSTRACT
Topical tretinoin is used in the treatment of acne and other dermatoses. The most common side-effects are itching, dryness and reddening of the skin. We report an additional cutaneous reaction, which occurred in patients using topical tretinoin. Pyogenic granulomas developed in two patients with acne and in one with dermatofibroma following application of tretinoin. The granulomas grew on the lesions after 2–3 weeks of therapy initiation. All patients were men and the granulomas developed in their trunk. The lesions resolved when topical tretinoin was ceased. Although the number of patients reported is too small to estimate the true incidence of this reaction, it is likely that dermatologists will encounter similar reactions in patients treated with topical tretinoin for acne or other reasons. Received: 18 February 2002, accepted 19 July 2002 | 
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