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Wiley InterScience | |||||||||||||
  Journal of the European Academy of Dermatology and VenereologyVolume 18 Issue 5, Pages 586 - 587 Published Online: 16 Jun 2004 Journal compilation © 2010 European Academy of Dermatology and Venereology Published on behalf of the European Academy of Dermatology and Venereology
Abstract | References | Full Text: HTML, PDF (Size: 89K) | Related Articles | Citation Tracking  CASE REPORT Fixed drug eruption from piroxicam Copyright © 2004 European Academy of Dermatology and Venereology KEYWORDS fixed drug eruption • piroxicam • patch test ABSTRACT
The pathogenetic mechanism of fixed drug eruption (FDE) is still unknown. One of the most common causes of FDE is the use of nonsteroidal antiinflammatory drugs (NSAIDs). Oxicams are in the NSAID group and piroxicam is one of the most used of these drugs. FDE caused by piroxicam is rare but a few cases have been reported. Patch tests are useful for diagnosing some cases of FDE; they give variable results on previously affected skin while no reaction appears on unaffected skin. Some cases of cross-sensitivity among piroxicam and other substances have been reported. We report two new cases of FDE due to piroxicam with negative patch test on normal skin and positive results on affected skin. Accepted 20 June 2003 | 
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