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Review article
Schizophrenia and weight management: a systematic review of interventions to control weight
G. Faulkner 1 , A. A. Soundy 2 , K. Lloyd 3
  1 Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada ,   2 Department of Exercise and Sport Science, School of Sport and Health Sciences, University of Exeter, Exeter, UK and   3 Peninsula Medical School, Mental Health Research, Exeter, UK
Correspondence to Guy Faulkner, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, M55 2W6, Canada
E-mail: guy.faulkner@utoronto.ca
Copyright 2003 Blackwell Munksgaard
KEYWORDS
weight loss • schizophrenia • review
Faulkner G, Soundy AA, Lloyd K. Schizophrenia and weight management: a systematic review of interventions to control weight.
Acta Psychiatr Scand 2003: 108: 324–332. © Blackwell Munksgaard 2003.

ABSTRACT

Objective: Weight gain is a frequent side effect of antipsychotic medication which has serious implications for a patient's health and well being. This study systematically reviews the literature on the effectiveness of interventions designed to control weight gain in schizophrenia.

Method: A systematic search strategy was conducted of major databases in addition to citation searches. Study quality was rated.

Results: Sixteen studies met the inclusion criteria. Five of eight pharmacological intervention studies reported small reductions in weight (<5% baseline body weight). All behavioural (including diet and/or exercise) interventions reported small reductions in, or maintenance of, weight.

Conclusion: Weight loss may be difficult but it is not impossible. Given the inconsistent results, the widespread use of pharmacological interventions cannot be recommended. Both dietary and exercise counselling set within a behavioural modification programme is necessary for sustained weight control.


Accepted for publication June 30, 2003

DIGITAL OBJECT IDENTIFIER (DOI)
10.1034/j.1600-0447.2003.00218.x About DOI

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