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Wiley InterScience

Clinical Microbiology and Infection

Clinical Microbiology and Infection

Volume 9 Issue 11, Pages 1112 - 1115

Published Online: 31 Oct 2003

Journal compilation © 2010 European Society of Clinical Microbiology and Infectious Diseases



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Concise Communication
Fusobacterium nucleatum: a rare cause of bacteremia in neutropenic patients with leukemia and lymphoma
A. Candoni 1 , C. Filì 1 , R. Trevisan 2 , F. Silvestri 1 and R. Fanin 1
  1 Division of Hematology and Bone Marrow Transplantation, Department of Medical and Morphological research, University Hospital and   2 Institute of Microbiology, General Hospital, Udine, Italy
Corresponding author and reprints requests: Dr A. Candoni, Division of Hematology, University Hospital, P.le S. Maria della Misericordia, 33100 Udine, Italy
Tel: +39 432 559662
Fax: +39 432 559661
E-mail: candoni.a@tiscali.it
Copyright © 2003 Copyright by the European Society of Clinical Microbiology and Infectious Diseases
KEYWORDS
Fusobacterium nucleatum • neutropenia • bacteremia • anaerobes

ABSTRACT

Although anaerobic bacteremias are uncommon in oncohematologic patients, nevertheless they have been considered an emergent problem in the last few years. Fusobacterium nucleatum is an anaerobic Gram-negative bacillus commonly present in the oral cavity and in the respiratory and genito-urinary tracts. Over a 10-year period 18 episodes of F. nucleatum bacteremia in patients with hematological malignances (15 leukemias and 3 lymphomas) have been observed in our Department of Hematology. Predisposing factors included oropharyngeal mucositis and severe neutropenia owing to intensive chemotherapy. In our experience no septic shock occurred and the outcome of bacteremias caused by F. nucleatum was favorable.


Accepted 26 December 2002

DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1469-0691.2003.00717.x About DOI

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