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Wiley InterScience

British Journal of Dermatology

British Journal of Dermatology

Volume 148 Issue 6, Pages 1263 - 1266

Published Online: 27 Jun 2003

Journal compilation © 2010 British Association of Dermatologists



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CASE REPORT
Congenital adrenal hyperplasia and acne in male patients
K. Degitz , M. Placzek , B. Arnold , H. Schmidt* and G. Plewig
 Department of Dermatology and   *Department of Paediatrics, Ludwig-Maximilian-University, München, Germany
Correspondence to Dr K.Degitz, Department of Dermatology, Ludwig-Maximilian-University, Frauenlobstrasse 9-11, D-80337 München, Germany. E-mail: klaus.degitz@lrz.uni-muenchen.de
Copyright 2003 British Association of Dermatologists
KEYWORDS
acne vulgaris • congenital adrenal hyperplasia • hyperandrogenism

ABSTRACT

Summary Seborrhoea is one pathogenic factor for acne. Androgens induce sebum production, and excess androgen may provoke or aggravate acne. In women an androgen disorder is frequently suspected when acne is accompanied by hirsutism or menstrual irregularities. In men acne may be the only symptom of androgen excess. We report three male acne patients in whom hormonal screening revealed irregularities of androgen metabolism suggestive of late-onset congenital adrenal hyperplasia and who benefitted from low-dose glucocorticoids. Disorders of androgen metabolism may influence acne not only in women, but also in men, and these patients may benefit from low-dose glucocorticoid therapy.


Accepted for publication 19 November 2002

DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1365-2133.2003.05369.x About DOI

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