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Wiley InterScience | |||||||
  Dermatologic SurgeryVolume 29 Issue 4, Pages 429 - 432 Published Online: 26 Mar 2003 © 2010 American Society of Dermatologic Surgery
Abstract | References | Full Text: HTML, PDF (Size: 415K) | Related Articles | Citation Tracking  CASE REPORT Lip Silicone Granulomatous Foreign Body Reaction Treated With Aldara (Imiquimod 5%) Copyright © 2003 by the American Society for Dermatologic Surgery, Inc. L. S. BAUMANN, MD, AND M. L. HALEM, MD HAVE INDICATED NO SIGNIFICANT INTEREST WITH COMMERCIAL SUPPORTERS. ABSTRACTWe report a case of a lip granulomatous reaction after injection of silicone being treated successfully with topical Aldara (Imiquimod 5%). Silicone granulomas and the inflammatory foreign body reaction that can occur are some of the complications that arise from using silicone for cosmetic enhancement. The inflammatory reaction of this patient first appeared shortly after silicone injection of both the upper and lower lips. Histopathologic examination revealed a foreign body inflammatory reaction that is consistent with silicone granuloma. Although this reaction has been described extensively in the dermatologic literature as one of the disfiguring side effects of silicone injection, its treatment has plagued cosmetic dermatologists. We report the use of an immunomodulatory cream Aldara (Imiquimod 5%) to treat this type of reaction. | 
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