ADVERTISEMENT

If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.

It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.

Wiley InterScience

< Previous Abstract  |  Next Abstract >

Save Article to My Profile      Download Citation      Request Permissions

Abstract |  References  |  Full Text: HTML, PDF (Size: 83K)  | Related Articles | Citation Tracking

Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel
Isabelle Uhoda 1 , Najat Faska 1 , Caroline Robert 2 , Geert Cauwenbergh 3 and Gérald. E. Piérard 1
  1 Unit of Dermocosmetology Department of Dermatopathology University Medical Center of Liège, Belgium,   2 Johnson & Johnson Consumers, Paris, France and   3 Johnson & Johnson, New Brunswick, USA
Correspondence to Gérald E. Piérard
Department of Dermatopathology
CHU Sart Tilman
B-4000 Liège
Belgium

Tel: + 32 4 3662408
Fax: + 32 4 3662976
e-mail: Gerald.Pierard@ulg.ac.be
Copyright © Blackwell Munksgaard, 2002
KEYWORDS
Dimethylaminoethanol • shear wave propagation • tensile strength • acetylcholine

ABSTRACT

Background/aims:Beyond subjective assessments, the effect of skin tensors is difficult to assess. The present 2-phase randomized double-blind split face study was designed to compare the effect of a gel containing 3% 2-dimethylaminoethanol (deanol, DMAE) with the same formulation without DMAE.

Methods:In a first pilot study, sensorial assessments and measures of the skin distension under suction were performed in eight volunteers. In a second study conducted in 30 volunteers, shear wave propagation was measured.

Results:Large interindividual variations precluded any significant finding in the first study. The DMAE formulation showed, however, a significant effect characterized by increased shear wave velocity in the direction where the mechanical anisotropy of skin showed looseness.

Conclusion:The DMAE formulation under investigation increased skin firmness.


Accepted for publication 22 May 2001

DIGITAL OBJECT IDENTIFIER (DOI)
10.1034/j.1600-0846.2002.10295.x About DOI

Related Articles

  • Find other articles like this in Wiley InterScience
  • Find articles in Wiley InterScience written by any of the authors

Wiley InterScience is a member of CrossRef.

Cross Ref Member


Sign Up Now
Sign Up Now
Sign Up Now
Wiley Medical Twitter