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Wiley InterScience

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Cytometric Evaluation of Peripheral Blood Lymphocytes in Dogs with Lymphoma during Chemotherapy
A. Winnicka 1,2 , D. Jagielski 1 , M. Hoffmann-Jagielska 1 and R. Lechowski 1
  1 Department of Internal Diseases, Faculty of Veterinary Medicine, Grochowska 272, Warsaw, Poland;
  2 Corresponding author:
E-mail:winnicka@amaltea.sggw.waw.pl
Agricultural University of Warsaw, Warsaw, Poland
Copyright 2002 Blackwell Verlag, Berlin

Summary

AbstractIntroductionMaterials and MethodsResults and discussionReferences

Twenty dogs with clinically diagnosed multicentric lymphoma were evaluated for percentages of peripheral blood lymphocyte subpopulations. Cytometric analysis was performed before and during chemotherapy. The results were compared to those obtained from a control group of healthy dogs. The percentages of CD5+, CD4+ and CD8+ cells were markedly decreased and CD21-like+ cellsmarkedly increased in dogs with lymphoma in comparison withthe control group. During the course of chemotherapythese values returned to ranges observed in healthy animals.


With 3 tables Received for publication November 16, 2001

DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1439-0442.2002.00455.x About DOI

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