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Wiley InterScience | ||||||
  CephalalgiaVolume 22 Issue 3, Pages 186 - 189 Published Online: 5 Jun 2002 © 2009 International Headache Society Published on behalf of the International Headache Society
Abstract | References | Full Text: HTML, PDF (Size: 51K) | Related Articles | Citation Tracking  Treatment of cluster headache with topiramate: effects and side-effects in five patients Copyright Blackwell Science, 2002 KEYWORDS Cluster headache • side-effects • therapy • topiramate Förderreuther S, Mayer M & Straube A. Treatment of cluster headache with topiramate: effects and side-effects in five patients. Cephalalgia 2002; 22:186–189. London. ISSN 0333-1024 ABSTRACTWe report on clinical experience with topiramate in the prophylactic treatment of three patients with chronic and two patients with episodic, otherwise therapy-resistant, cluster headache. Patients were treated with daily doses of 75–200 mg topiramate. Topiramate was effective in three patients but proved ineffective and also caused intolerable side-effects in two patients. Topiramate may have prophylactic properties for treating cluster headache at lower doses than needed in epilepsy therapy, but its clinical value is limited due to central nervous system side-effects. Received 24 October 2001, accepted 5 December 2001 | 
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