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Wiley InterScience

Biometrics

Biometrics

Volume 57 Issue 1, Pages 182 - 188

Published Online: 24 May 2004

©2009 International Biometric Society



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Estimation of Population Attributable Fractions from Fitted Incidence Ratios and Exposure Survey Data, with an Application to Electromagnetic Fields and Childhood Leukemia
Sander Greenland 1
  1 Department of Epidemiology, UCLA School of Public Health, and Department of Statistics, UCLA College of Letters and Science Los Angeles, California 90095-1772, U.S.A.
Copyright The International Biometric society, 2001
KEYWORDS
Attributable fraction • Attributable risk • Bootstrap • Epidemiological methods • Population attributable risk • Probability of causation • Relative risk • Risk assessment • Risk regression

Summary.

AbstractReferences

Summary. Standard presentations of epidemiological results focus on incidence-ratio estimates derived from regression models fit to specialized study data. These data are often highly nonrepresentative of populations for which public-health impacts must be evaluated. Basic methods are provided for interval estimation of attributable fractions from model-based incidence-ratio estimates combined with independent survey estimates of the exposure distribution in the target population of interest. These methods are illustrated in estimation of the potential impact of magnetic-field exposures on childhood leukemia in the United States, based on pooled data from 11 case-control studies and a U.S. sample survey of magnetic-field exposures.


Received September 1999. Revised May 2000. Accepted June 2000.

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.0006-341X.2001.00182.x About DOI

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