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Wiley InterScience

Biometrics

Biometrics

Volume 57 Issue 3, Pages 853 - 860

Published Online: 21 May 2004

©2009 International Biometric Society



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Accelerated Hazards Regression Model and Its Adequacy for Censored Survival Data
Ying Qing Chen 1
  1 Division of Biostatistics, School of Public Health, University of California, 140 Warren Hall, 7360, Berkeley, California 94720, U.S.A. email:yqchen@stat.berkeley.edu
Copyright The International Biometric Society, 2001
KEYWORDS
Accelerated hazards • Diagnostic • Regression • Scale change • Survival data

Summary.

AbstractReferences

Summary. The accelerated hazards regression model is introduced to study the relationship between survival times and covariates through a scale change between hazard functions. The model is also compared with several other popular classes of regression models for censored survival data in statistical literature. Test statistics are proposed and studied to assess the model's adequacy. Actual data from a randomized clinical trial of biodegradable carmustine polymer for treatment of brain cancer are analyzed to demonstrate the potential application of the regression model and the proposed test statistics.

Received July 2000. Revised February 2001. Accepted March 2001.

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.0006-341X.2001.00853.x About DOI

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