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Wiley InterScience

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 107 Issue 1, Pages 133 - 134

Published Online: 12 Aug 2005

Journal compilation © 2010 RCOG



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B cell leukaemia/lymphoma-2 protein concentrations during normal pregnancy
M. Buemi Associate Professor (Nephrology) * , A. Allegra Medical Doctor * , F. Corica Medical Doctor * , R. D'Anna Medical Doctor ** , A. Ruello Medical Doctor * , V. M. Jasonni Associate Professor (Obstetrics and Gynaecology) **
  * Chair of Nephrology, Department of Internal Medicine   ** Institute of Obstetrics and Gynaecology, University of Messina, Italy
  Correspondence: Professor M. Buemi, Via Salita Villa Contino 30, 98100 Messina, Italy.
Copyright RCOG 2000 British Journal of Obstetrics and Gynaecology

ABSTRACT

We evaluated bcl-2 protein levels in whole blood, and intraerythrocytic products of lipoperoxidation, in 65 healthy pregnant primiparous women at the end of the first, second and third trimesters of pregnancy. During pregnancy we found a progressive increase in concentrations of bcl-2 and intraerythrocytic products of lipoperoxidation. Moreover, a positive correlation was found between bcl-2 concentrations and lipoperoxidation products, and between bcl-2 protein, E2 and progesterone. The results show that modifications occurring during pregnancy are accompanied by variations of bcl-2 protein.


Accepted 29 June 1999

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1471-0528.2000.tb11591.x About DOI

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