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Wiley InterScience

Psychiatry and Clinical Neurosciences

Psychiatry and Clinical Neurosciences

Volume 53 Issue 4, Pages 535 - 537

Published Online: 4 Jan 2002

Journal compilation © 2010 Japanese Society of Psychiatry and Neurology



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Lithium and clonazepam treatment of two cases with cluster headache
Minoru Takebayashi, MD, PhD , 1 Tokumi Fujikawa, MD, PhD , 2 Ariyuki Kagaya, MD, PhD , 1 Jun Horiguchi, MD, PhD , 1 and Shigeto Yamawaki, MD, PhD 1
  1 Department of Psychiatry and Neurosciences, Hiroshima University School of Medicine, Hiroshima and   2 National Sanatorium Kamo Hospital, Hiroshima, Japan
 Correspondence address: ProfessorShigetoYamawaki
Copyright 1999 Blackwell Science Asia Pty. Ltd.
KEYWORDS
clonazepam • cluster headache • lithium

ABSTRACT

 

Abstract

Patients with cluster headache are often treated with lithium. However, there are some patients who can not be fully treated with lithium alone. Two patients with cluster headache were treated with clonazepam, one of the most potent benzodiazepines. Lithium prolonged the period of remission, and the addition of clonazepam further prolonged it in case 1. Treatment with clonazepam reduced the symptoms in case 2, and when combined with lithium, the disorder went into remission after 6 months. These findings suggest that the combination of lithium and clonazepam may be effective in patients with cluster headache.


DIGITAL OBJECT IDENTIFIER (DOI)
10.1046/j.1440-1819.1999.00573.x About DOI

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