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Wiley InterScience | ||||||||||
  AnaesthesiaVolume 53 Issue 8, Pages 808 - 809 Published Online: 6 Apr 2002 Journal compilation © 2010 The Association of Anaesthetists of Great Britain and Ireland Journal of the Association of Anaesthetists of Great Britain and Ireland
Abstract | References | Full Text: HTML, PDF (Size: 333K) | Related Articles | Citation Tracking  The use of lamotrigine in neuropathic pain Copyright Blackwell Science Ltd KEYWORDS
Pain; pathological •
Pharmacology; lamotrigine ABSTRACTSodium channel antagonists have been used in the management of neuropathic pain for several years. Recent evidence suggests that lamotrigine, which is active at glutaminergic excitatory synapses, is very effective in producing pain relief. We have successfully used lamotrigine in two patients suffering from neuropathic pain. Our results suggest that this novel channel antagonist can be used to treat neuropathic pain. Double blind placebo control studies are therefore needed to substantiate these findings.
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