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Wiley InterScience | |||||||
  Journal of Internal MedicineVolume 240 Issue 6, Pages 403 - 404 Published Online: 31 Oct 2003 © 2010 Blackwell Publishing Ltd
Abstract | Full Text: PDF (Size: 111K) | Related Articles | Citation Tracking  Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil KEYWORDS simvastatin • gemfibrozil • adverse effect • rhabdomyolysis ABSTRACTThe occurrence of rhabdomyolysis is one of the rare side-effects of the cholesterol-lowering agent simvastatin. During the use of lovastatin, an agent related to simvastatin, the risk of this side-effect might be increased when cyclosporin or gemfibrozil are used concomitantly. It is possible that this also applies for simvastatin. We present two patients who developed rhabdomyolysis during the concomitant use of simvastatin and gemfibrozil.
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