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Wiley InterScience | |||||||||
  British Journal of DermatologyVolume 132 Issue 5, Pages 762 - 765 Published Online: 29 Jul 2006 Journal compilation © 2010 British Association of Dermatologists An Official Journal of the British Association of Dermatologists
Abstract | References | Full Text: PDF (Size: 1544K) | Related Articles | Citation Tracking  The effects of topical indomethacin and clobetasol propionate on post-cryotherapy inflammation Copyright 1995 British Association of Dermatologists ABSTRACT
The effects of topical indomethacin and clobetasol propionate on erythema and oedema following lowdose cryotherapy to normal skin were examined using a single-blind technique. Both agents significantly reduced erythema, but neither had a significant effect on oedema. A further, controlled, double-blind study comparing topical indomethacin and inert gel base was performed after cryotherapy to hand warts. In this study, topical indomethacin had no significant effect on post-cryotherapy oedema, erythema, pain or blister formation 48 and 96 h after treatment. Both potent topical steroids and cyclo-oxygenase inhibitors reduce erythema after low-dose cryotherapy. In clinical practice, there is no evidence that topical indomethacin significantly inhibits the inflammatory response to cryotherapy. Accepted for publication 26 July 1994 | 
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