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Wiley InterScience | ||||||||||
  Headache: The Journal of Head and Face PainVolume 35 Issue 5, Pages 256 - 259 Published Online: 18 May 2005 © 2010 American Headache Society Published on behalf of the American Headache Society
Abstract | Full Text: PDF (Size: 40K) | Related Articles | Citation Tracking  Comparison of Dihydroergotamine With Metoclopramide Versus Meperidine With Promethazine in the Treatment of Acute Migraine Copyright © 1995 American Headache Society (formerly the American Association for the Study of Headache) KEYWORDS migraine • headache • dihydroergotamine • metoclopramide • meperidine • promethazin ABSTRACTMigraineurs often seek office-based treatment for acute headache. To compare the efficacy and side effect profile, we entered 27 migraineurs into a prospective, randomized, double-blind study where each patient received either 75 mg meperidine with 25 mg promethazine IM or .5 mg dihydroergotamine with 10 mg metoclopramide IV. After I hour, pain relief was similar in the two groups, but side effects were significantly greater in the meperidine with promethazine regimen group. The dihydroergotamine with metoclopramide regimen is effective, and has minimal side effects, making it an attractive method for office-based treatment of acute migraine. Accepted for publication November 14, 1994. | 
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