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Wiley InterScience | |||||||||||||
  Journal of the American Ceramic SocietyVolume 74 Issue 7, Pages 1487 - 1510 Published Online: 8 Mar 2005 © 2010 American Ceramic Society Published on behalf of the American Ceramic Society (ACerS)
Abstract | References | Full Text: PDF (Size: 2705K) | Related Articles | Citation Tracking  Bioceramics: From Concept to Clinic R. E. Newnham—contributing editor Supported by U.S. Air Force Office of Scientific Research under Contract No. F496290-88-C-0073. The conducted research was reviewed and approved by the University of Florida Institutional Animal Care and Use Committee to ensure that the research procedures adhered to the standards set forth in the Guide for the Care and Use of Laboratory Animals (NIH Publication 85–23) as promulgated by the Committee on Care and Use of Laboratory Animals of the Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council.
Copyright 1991 by The American Ceramic Society KEYWORDS bioceramics • structure • dental ceramics • interfaces • mechanics ABSTRACTCeramics used for the repair and reconstruction of diseased or damaged parts of the musculo-skeletal system, termed bioceramics, may be bioinert (alumina, zirconia), resorbable (tricalcium phosphate), bioactive (hydroxyapatite, bioactive glasses, and glass-ceramics), or porous for tissue ingrowth (hydroxyapatite-coated metals, alumina). Applications include replacements for hips, knees, teeth, tendons, and ligaments and repair for periodontal disease, maxillofacial reconstruction, augmentation and stabilization of the jaw bone, spinal fusion, and bone fillers after tumor surgery. Carbon coatings are thromboresistant and are used for prosthetic heart valves. The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues. Composites are being developed with high toughness and elastic modulus match with bone. Therapeutic treatment of cancer has been achieved by localized delivery of radioactive isotopes via glass beads. Development of standard test methods for prediction of long-term (20-year) mechanical reliability under load is still needed. Manuscript No. 196865. Received March 3, 1991; approved April 23, 1991. | 
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