ADVERTISEMENT

If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.

It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.

Wiley InterScience

International Journal of Dermatology

International Journal of Dermatology

Volume 30 Issue 8, Pages 586 - 589

Published Online: 31 May 2007

Journal compilation © 2010 International Society of Dermatology



< Previous Abstract  |  Next Abstract >

Save Article to My Profile      Download Citation      Request Permissions

Abstract |  References  |  Full Text: PDF (Size: 5065K)  | Related Articles | Citation Tracking

Onychomycosis Treated with Itraconazole or Griseofulvin Alone with and without a Topical Antimycotic or Keratolytic Agent
Roberto Arenas, M.D. 1 , Genoveva Fernández, M.D., 1 Luciano Dornínguez, M.D. 1
  1 From the Departamento de Dermatologia, Hospital General "Dr. Manuel Gea González," Mexico.
 Address correspondence to: Roberto Arenas, M.D., Departamento de Dermatologia, Hospital General "Dr. Manuel Gea González," Tlalpan 4800, Mexico D.F. C.P. 14000.
Copyright 1991 Blackwell Science Ltd

ABSTRACT

AbstractReferences

Abstract: An open, comparative, randomized study was conducted using griseofulvin or itraconazole for the treatment of onychomycosis of the foot. Group I (45 patients) received itraconazole and Group II (45 patients) received griseofulvin. Each group was divided into three subgroups that received different topical treatment: antimycotic cream (isoconazole 1%), keratolytic cream (urea 40%), or placebo cream. The itraconazole group showed complete clearance in combination with isoconazole cream in 73.3% (11 of 15 patients), in combination with keratolytic cream in 78.5% (11 of 14 patients), and in combination with placebo cream in 91.6% (11 of 12 patients). The griseofulvin group showed complete clearance in combination with isoconazol cream in 46.1% (7 of 15 patients), in combination with keratolytic cream in 42.8% (6 of 15 patients), and in combination with placebo cream in 26.6% (4 of 15 patients). The itraconazole group showed better results compared with the griseofulvin group when the chi-square statistical method was used.


DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1365-4362.1991.tb02648.x About DOI

Related Articles

  • Find other articles like this in Wiley InterScience
  • Find articles in Wiley InterScience written by any of the authors

Wiley InterScience is a member of CrossRef.

Cross Ref Member


Sign Up Now
Sign Up Now
Sign Up Now
Wiley Medical Twitter