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Wiley InterScience | |||||||||
  Contact DermatitisVolume 24 Issue 2, Pages 89 - 93 Published Online: 11 Apr 2006 © 2010 John Wiley & Sons A/S
Abstract | References | Full Text: PDF (Size: 470K) | Related Articles | Citation Tracking  Contact sensitivity to miconazole with ortho-chloro cross-sensitivity to other imidazoles Copyright Munksgaard 1991 KEYWORDS miconazole • cross-sensitivity • antimycotics • triazoles • ortho-chloro allergy • contact allergy • imidazoles • azoles • medicaments ABSTRACTA case of allergic contact dermatitis from miconazole is reported. Patch testing with a series of azole antimycotics was positive only to miconazole, isoconazole, tioconazole and oxiconazole. Those reacting are all β-substituted 1-phenethyl imidazoles with an ortho-chlorine substitution on the aromatic ring. For this hitherto unreported pattern of cross-sensitivity, the designation of "orthochloro cross-sensitivity" is proposed. Accepted for publication 30 July 1990 | 
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