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Wiley InterScience | ||||||||
  Clinical and Experimental DermatologyVolume 16 Issue 1, Pages 55 - 57 Published Online: 27 Apr 2006 Journal compilation © 2010 British Association of Dermatologists An Official Journal of the British Association of Dermatologists
Abstract | References | Full Text: PDF (Size: 171K) | Related Articles | Citation Tracking  Minocycline-induced pigmentation occurring in two sisters Copyright 1991 Blackwell Science Ltd ABSTRACT
Two sisters are described who developed facial pigmentation while on minocycline therapy for acne vulgaris. It is suggested that the possible mechanisms for this relatively uncommon complication occurring in these two patients may be due to either a genetically acquired alteration in metabolic handling of minocycline or to the ethinyl-oestradiol component of Dianette, which they were also receiving as treatment for their acne vulgaris. It is concluded that patients on minocycline should be regularly screened for signs of hyperpigmentation, especially if they are on other drugs which are known to accentuate pigmentation of skin. Accepted for publication 10 July 1990 | 
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