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Wiley InterScience | ||||||||||||
  AnaesthesiaVolume 45 Issue 11, Pages 916 - 919 Published Online: 22 Feb 2007 Journal compilation © 2010 The Association of Anaesthetists of Great Britain and Ireland Journal of the Association of Anaesthetists of Great Britain and Ireland
Abstract | References | Full Text: PDF (Size: 314K) | Related Articles | Citation Tracking  Platelet function after intramuscular diclofenac Copyright 1990 The Association of Anaesthetists of Great Britain and Ireland KEYWORDS
Analgesics; diclofenac •
Blood; coagulation ABSTRACT
A randomised double-blind controlled study was performed to examine the effect of diclofenac on skin bleeding time and in vitro whole blood platelet aggregation. Twenty thoracotomy patients were studied; 10 were given diclofenac 75 mg intramuscularly at induction of anaesthesia, and 10 formed a control group. Skin bleeding times and platelet aggregation tests were performed the day before and repeated one hour after induction of anaesthesia. Diclofenac prolonged skin bleeding time and reduced platelet aggregation. There were no significant changes in the control group. Accepted 29 March 1990 | 
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