Comorbidity of headache and gastrointestinal complaints. The Head-HUNT Study

doi:10.1111/j.1468-2982.2007.01486.x

If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.

It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.

Systems Maintenance, Monday, 15th February 2010

Wiley InterScience

Cephalalgia

Volume 28 Issue 2, Pages 144 - 151

Published Online: 9 Jan 2008

Published on behalf of the International Headache Society

Go to Society Site

< Previous Abstract | Next Abstract >

Save Article to My Profile Download Citation Request Permissions

Abstract | References | Full Text: HTML, PDF (Size: 103K) | Related Articles | Citation Tracking

Comorbidity of headache and gastrointestinal complaints. The Head-HUNT Study

AH Aamodt, LJ Stovner, K Hagen & J-A Zwart

Norwegian National Headache Centre, Trondheim University Hospital, Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Norway

Correspondence to Anne Hege Aamodt, MD, Norwegian National Headache Centre, Trondheim University Hospital, Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, N-7006 Trondheim, Norway. Tel. + 47 7257 6006, fax + 47 7257 5773, e-mail anne.hege.aamodt@ntnu.no

KEYWORDS

Migraine • headache • gastrointestinal complaints • epidemiology • HUNT

Aamodt AH, Stovner LJ, Hagen K & Zwart J-A. Comorbidity of headache and gastrointestinal complaints. The Head-HUNT Study. Cephalalgia 2008; 28:144–151. London. ISSN 0333-1024

ABSTRACT

Associations between headache, including migraine, and gastrointestinal (GI) symptoms were studied in a large questionnaire-based cross-sectional study (the Head-HUNT Study). The headache questionnaire was completed by 43 782 individuals, who answered all the questions concerning nausea, reflux symptoms, diarrhoea and constipation. In the multivariate analyses, adjusting for age, sex, educational level, medication use, depression and anxiety, a higher prevalence of headache was found in individuals with much reflux [odds ratio (OR) 2.4, 95% confidence interval (CI) 2.2, 2.6], diarrhoea (OR 2.4, 95% CI 2.1, 2.8), constipation (OR 2.1, 95% CI 1.9, 2.4) and nausea (OR 3.2, 95% CI 2.6, 3.8) compared with those without such complaints. All the GI symptoms investigated seemed to be approximately as common among persons with non-migrainous headache as among migraine sufferers, but the association between headache and GI complaints increased markedly with increasing headache frequency. This may suggest that headache sufferers generally are predisposed to GI complaints.

Received 20 October 2006, accepted 12 July 2007

DIGITAL OBJECT IDENTIFIER (DOI)

10.1111/j.1468-2982.2007.01486.x About DOI