|
If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.
It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.
Wiley InterScience | ||||||||||||
  Sleep and Biological RhythmsVolume 6 Issue 2, Pages 67 - 75 Published Online: 21 Apr 2008 Journal compilation © 2009 Japanese Society of Sleep Research The official English language journal of the Japanese Society of Sleep Research
Abstract | References | Full Text: HTML, PDF (Size: 189K) | Related Articles | Citation Tracking  REVIEW ARTICLE For whom the bells toll: Networked circadian clocks Copyright Journal compilation © 2008 Japanese Society of Sleep Research KEYWORDS computational model • Period gene • suprachiasmatic nucleus •
Synechococcus
• vasoactive intestinal polypeptide ABSTRACT
Circadian cycles are robust and precise biological rhythms common in unicellular and multicellular organisms. Single cells have been shown to sustain autonomous near 24-h rhythms, however, many cells and tissues appear to require cell–cell interactions to maintain periodicity. This review highlights the mechanisms and benefits of coupling circadian oscillators. We focus on how populations of circadian oscillators synchronize in a variety of biological systems and describe recent efforts to model mathematically coupling and synchrony in the mammalian suprachiasmatic nucleus. We conclude by discussing the effects of disrupted circadian coupling on health and behavior. Accepted for publication 16 March 2008. | 
|
