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Wiley InterScience | ||||||||||||
  AnaesthesiaVolume 44 Issue 1, Pages 57 - 60 Published Online: 22 Feb 2007 Journal compilation © 2010 The Association of Anaesthetists of Great Britain and Ireland Journal of the Association of Anaesthetists of Great Britain and Ireland
Abstract | References | Full Text: PDF (Size: 407K) | Related Articles | Citation Tracking  Failure of rectal diclofenac to augment opioid analgesia after cholecystectomy Copyright 1989 The Association of Anaesthetists of Great Britain and Ireland KEYWORDS
Analgesia, postoperative
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Analgesics; diclofenac ABSTRACT
The analgesic efjcacy of a single 100-mg suppository of diclofenac sodium given after elective cholecystectomy was studied in 30 healthy patients in a double-blind randomised controlled manner. The mean 24-hour postoperative morphine consumption of the placebo group and the diclofenac group was similar (45 mg). Analysis of the cumulative hourly morphine consumption from the patient-controlled analgesia system failed to show any statistically significant differences between the groups. Peak expiratory flow rate, forced expiratory volume at I second and forced vital capacity decreased 24 hours after operation to less than 50% of pre-operative values in both groups. Subjective experiences of pain, nausea and drowsiness assessed by linear analogue scoring were similar in both groups. Accepted 16 June 1988. | 
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