|
If you are seeing this message, you may be experiencing temporary network problems. Please wait a few minutes and refresh the page. If the problem persists, you may wish to report it to your local Network Manager.
It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the latest version of Microsoft or Mozilla web browser to help minimise these problems.
Wiley InterScience | |||||
  Journal of Human Nutrition and DieteticsVolume 2 Issue 2, Pages 105 - 116 Published Online: 28 Mar 2008 © 2010 The British Dietetic Association Published on behalf of the British Dietetic Association
Abstract | References | Full Text: PDF (Size: 913K) | Related Articles | Citation Tracking  The problem of rickets in UK Asians Copyright 1989 British Dietetic Association KEYWORDS Asian rickets • vitamin D • sunlight • Pigmentation • enterohepatic circulation • Phytate • cereals • calcium metabolism disorders • 25-hydroxyvitamin D • hyperparathyroidism • 1 • 25-dihydroxyvitamin D ABSTRACTA large body of work relating to the occurrence of rickets in UK Asians is reviewed. Several theories of the aetiology of this condition are shown to be untenable: it is not exclusively a function of sunlight deprivation or of darker pigmentation; nor is it simply due to phytate-induced losses of calcium from the gut. Asian rickets, however, is associated with a high consumption of cereals, and experiments with rats have suggested a mechanism. In the absence of adequate vitamin D from sunlight, the low-calcium, high cereal intake of the UK Asian population may induce a state of mild secondary hyperparathyroidism which enhances the destruction of vitamin D and leads to a progressive reduction in vitamin D status and, ultimately, to the development of clinical rickets. | 
|
