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Wiley InterScience | ||||||||
  Australasian Journal of DermatologyVolume 29 Issue 3, Pages 135 - 139 Published Online: 28 Jun 2007 Journal compilation © 2010 The Australasian College of Dermatologists
Abstract | References | Full Text: PDF (Size: 379K) | Related Articles | Citation Tracking  SPIRONOLACTONE THERAPY IN HIRSUTISM AND ACNE Copyright 1988 Blackwell Science Asia Pvt. Ltd. KEYWORDS Hirsutism • acne • spironolactone • anti-androgen ABSTRACT
Spironolactone has been found to have anti-androgenic properties and to be useful in the treatment of female hirsulism. Benefits have also been noted in the treatment of mature age onset or persistent acne in females. The mechanism of action of this drug is mainly via a peripheral anti-androgenic effect but it may also result in decreased androgen production. The results of a number of clinical studies are discussed with particular reference to the side effects of spironolactone. Guidelines for treatment of hirsutism and female mature age acne are given. | 
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