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Wiley InterScience

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 95 Issue 7, Pages 654 - 658

Published Online: 19 Aug 2005

Journal compilation © 2010 RCOG



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Short-term reproductive prognosis when no cause can be found for recurrent miscarriage
FABIO PARAZZINI 1 , BARBARA ACAIA 2 , ORIETTA RICCIARDIELLO 2 , LUIGI FEDELE 2 , PAOLA LIATI 1 , G. BATTISTA CANDIANI 2
  1 Istituto di Ricerche Farmacologiche 'Mario Negri', Via Eritrea 62,20157 Milan, Italy   2 I° Clinica Ostctriea e Ginecologica, Università di Milano, Via Commenda 12,20100 Milan, Italy
 Correspondence: Fabio Parazzini, MD
Copyright RCOG 1988 BJOG: an International Journal of Obstetrics and Gynaecology

ABSTRACT

Summary. The short-term reproductive prognosis of recurrent miscarriage for which no cause was found has been evaluated in 95 couples investigated between 1980 and 1986 at the First Obstetric and Gynaecological Clinic of the University of Milan. The actuarial overall 3-year livebirth delivery rate was 64%, increasing constantly with time. The reproductive success rate decreased with the number of previous miscarriages from 80% in women with two, to 60% with three and 46% with four or more miscarriages. No effect of age and socio-economic status emerged. There was a positive association between the number of previous miscarriages and the risk of miscarriage in the next pregnancy. Compared with women with two miscarriages the relative risk of another miscarriage was 2·3 for those with three previous miscarriages and 5·0 for those with four or more (χ21 for trend adjusted for age = 5·2, P= 0·02).


Received 13 July 1987, Accepted 9 March 1988

DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1471-0528.1988.tb06525.x About DOI

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