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Wiley InterScience | ||||||||||
  Headache: The Journal of Head and Face PainVolume 27 Issue 7, Pages 372 - 374 Published Online: 22 Jun 2005 © 2010 American Headache Society Published on behalf of the American Headache Society
Abstract | Full Text: PDF (Size: 91K) | Related Articles | Citation Tracking  Atenolol in Migraine Prophylaxis a Double-blind Cross-over Multicentre Study Copyright © 1987 American Headache Society (formerly the American Association for the Study of Headache) ABSTRACTSYNOPSIS The prophylactic anti-migraine effect of atenolol was compared to placebo in a multicentre study on 63 patients with classical and/or common migraine. The study design was double-blind cross-over and patients were given atenolol 100 mg o.d. or matching placebo during a study treatment period of 24 weeks. The effect of atenolol was significantly better than that of placebo: integrated headache values were reduced in 70% of the patients (p = 0.004) and the proportion of days with headache was reduced in 59% of the patients (p = 0.010). Few side effects were reported with both atenolol and placebo. This study shows atenolol to be safe and effective in the prophylactic treatment of migraine. Accepted for Publication: July 10, 1987 | 
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