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Wiley InterScience | |||||||||
  British Journal of DermatologyVolume 114 Issue 6, Pages 729 - 732 Published Online: 29 Jul 2006 Journal compilation © 2010 British Association of Dermatologists An Official Journal of the British Association of Dermatologists
Abstract | References | Full Text: PDF (Size: 204K) | Related Articles | Citation Tracking  Exacerbation of pemphigus by rifampicin Copyright 1986 British Association of Dermatologists ABSTRACT
Rifampicin therapy caused exacerbation of skin lesions, rising serum pemphigus antibody titres, and decreased serum betamethasone levels in a 59-year-old man with pemphigus vulgaris. Exacerbation of pemphigus was confined to the period of rifampicin therapy and seems to be best explained by the effect of rifampicin on the metabolism of betamethasone. Physicians prescribing rifampicin for the treatment of tuberculosis should be aware of its potential to produce such an important adverse reaction. Accepted for publication 27 November 1985 | 
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