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Wiley InterScience | ||||||||||||||||||
  PsychophysiologyVolume 22 Issue 6, Pages 648 - 655 Published Online: 30 Jan 2007 Copyright © 2009 by the Society for Psychophysiological Research Published on behalf of the Society for Psychophysiological Research
Abstract | References | Full Text: PDF (Size: 705K) | Related Articles | Citation Tracking  Caffeine Affects Cardiovascular Responses to Stress This research was supported by a New Investigator Research Award, 5 R23 HL29968, from the National Heart, Lung, and Blood Institute. Data analysis was aided by the CLINFO Data Analysis System of Duke University (G.C.R.C.) supported by the Division of Research Resources of N.I.H. This study was presented in part at the Annual Meeting of the Society for Psychophysiological Research, September 1983. Copyright 1985 by The Society for Psychophysiological Research KEYWORDS Caffeine • Psychological stress • Cardiovascular reactivity • Blood pressure • Forearm blood flow • Type A behavior • Hypertension risks ABSTRACT
The effects of caffeine on cardiovascular activity at rest and during psychological stress were examined in 33 healthy male college students who did not normally ingest caffeinated products. Caffeine (250 mg) and placebo were administered double-blind in separate sessions. Heart rate, blood pressure, and forearm blood flow and vascular resistance were assessed at rest and during the stressful, competitive performance of a mental arithmetic task. Comparisons of caffeine and placebo sessions revealed that caffeine elevated resting blood pressure 4–6 mmHg, an effect which added to the elevation produced by stress. Caffeine did not affect resting forearm blood flow but potentiated the forearm blood flow response to stress and led to higher levels of flow during stress. No caffeine effects appeared in heart rate or in task performance. Family history of hypertension and Type A behavior were examined as potential modulating factors of caffeine effects but results were generally negative. These results suggest possible mechanisms through which caffeine could enhance the pathogenic effects of stress on the cardiovascular system. (Manuscript received January 2, 1985; accepted for publication July 1, 1985) | 
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