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Wiley InterScience

Anaesthesia

Anaesthesia

Volume 39 Issue 5, Pages 429 - 432

Published Online: 22 Feb 2007

Journal compilation © 2010 The Association of Anaesthetists of Great Britain and Ireland



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Oxazepam premedication in neurosurgical patients
The use of a fast-dissolving oral preparation of oxazepam as a pre-operative anxiolytic drug in neurosurgical patients
R. F. BARRETT 1 , P. D. JAMES 1 K. C. A. MACLEOD 1
  1 R.F. Barrett, MB, BS, FFARCS, Consultant Anaesthetist, Odstock Hospital, Salisbury, Wiltshire, P.D. James, MB, BS, BSc, FFARCS, Senior Registrar in Anaesthetics, Brompton Hospital, London, K.C.A. MacLeod, MB, BS, FFARCS, Consultant Anaesthetist, St. Mary's Hospital, Praed Street, London.
 Correspondence should be addressed to Dr P.D. James, Department of Anaesthetics, Brompton Hospital, Fulham Road, London SW3 6HP.

Work carried out at National Hospital for Nervous Diseases, Queen Square, London.

Copyright 1984 The Association of Anaesthetists of Great Britain and Ireland
KEYWORDS
Premedication • benzodiazepine. Surgery • neurosurgical

ABSTRACT

Abstract

In a double-blind study, a new fast-dissolving formulation of oxazepam used as sole premedicant in patients undergoing neurosurgery, was assessed with particular reference to its effect on the levels of anxiety, consciousness and orientation of the patients pre- and postoperatively. The results show that when given at least one hour pre-operatively the new preparation is a highly effective anxiolytic with minimal sedative or other side-effects, is convenient to administer and has high patient acceptability.


DIGITAL OBJECT IDENTIFIER (DOI)
10.1111/j.1365-2044.1984.tb07310.x About DOI

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