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Wiley InterScience | |||||||
  Clinical & Experimental AllergyVolume 13 Issue 5, Pages 487 - 493 Published Online: 27 Apr 2006 © 2010 Blackwell Publishing Ltd The Official Journal of the British Society for Allergy & Clinical Immunology
Abstract | References | Full Text: PDF (Size: 310K) | Related Articles | Citation Tracking  Induction of suppressor T cells in asthmatic children by theophylline treatment Copyright 1983 Blackwell Science Ltd ABSTRACT
The absolute T-cell numbers and function, and the T-suppressor-cell subset were tested in eleven children with extrinsic asthma prior to and 1 month after theophylline treatment. Low mean T-suppressor-cell number and function was found in the asthmatic children, which returned to normal levels and function after 1 month of theophylline treatment. A normal mean T-cell number was found in this group of children prior to, and 1 month after, theophylline treatment. An obvious correlation between the clinical severity of the asthma and the number of T suppressor cells was found. It is suggested that theophylline most probably activated the T suppressor cells in the asthmatic children. (Received 20 May 1982; accepted for publication 31 August 1982) | 
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