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Wiley InterScience | ||
![]() Contact DermatitisVolume 8 Issue 2, Pages 105 - 108 Published Online: 11 Apr 2006 © 2010 John Wiley & Sons A/S
Abstract | References | Full Text: PDF (Size: 394K) | Related Articles | Citation Tracking Disulfiram treatment of three patients with nickel dermatitis Copyright Munksgaard 1982 KEYWORDS Contact dermatitis • disulfiram treatment • nickel ABSTRACTDiethyldithiocarbamate chelates nickel and accelerates its excretion in the urine. Disulfiram (Antabuse®) splits into two molecules of sodium diethyldithiocarbamate after absorption. Oral administration of disulfiram tablets starting with 50 mg a day with a gradual increase in dosage to 100 mg not more than twice a day readily cleared the eczema in three patients with severe and long-standing nickel contact dermatitis. Received February 26, 1981 |